Targeting dormant micrometastases: rationale, evidence to date and clinical implications

In spite of decades of research, cancer survival has increased only modestly. This is because most research is based on models of primary tumors. Slow recognition has begun that disseminated, dormant cancer cells (micrometastatic cells) that are generally resistant to chemotherapy are the culprits i...

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Bibliographic Details
Main Authors: Robert E. Hurst, Anja Bastian, Lora Bailey-Downs, Michael A. Ihnat
Format: Article
Language:English
Published: SAGE Publishing 2016-03-01
Series:Therapeutic Advances in Medical Oncology
Online Access:https://doi.org/10.1177/1758834015624277