HDL-like-Mediated Cell Cholesterol Trafficking in the Central Nervous System and Alzheimer’s Disease Pathogenesis

HDL-like-Mediated Cell Cholesterol Trafficking in the Central Nervous System and Alzheimer’s Disease Pathogenesis

The main aim of this work is to review the mechanisms via which high-density lipoprotein (HDL)-mediated cholesterol trafficking through the central nervous system (CNS) occurs in the context of Alzheimer’s disease (AD). Alzheimer’s disease is characterized by the accumulation of extracellular amyloi...

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Bibliographic Details
Main Authors: Carla Borràs, Aina Mercer, Sònia Sirisi, Daniel Alcolea, Joan Carles Escolà-Gil, Francisco Blanco-Vaca, Mireia Tondo
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
Alzheimer’s disease
apolipoprotein E
cholesterol trafficking
HDL
cholesterol efflux
central nervous system
Online Access:https://www.mdpi.com/1422-0067/23/16/9356

Internet

https://www.mdpi.com/1422-0067/23/16/9356

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