A new approach for detecting adventitious viruses shows Sf-rhabdovirus-negative Sf-RVN cells are suitable for safe biologicals production

A new approach for detecting adventitious viruses shows Sf-rhabdovirus-negative Sf-RVN cells are suitable for safe biologicals production

Abstract Background Adventitious viral contamination in cell substrates used for biologicals production is a major safety concern. A powerful new approach that can be used to identify adventitious viruses is a combination of bioinformatics tools with massively parallel sequencing technology. Typical...

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Bibliographic Details
Main Author: Christoph Geisler
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Biotechnology
Subjects:
Adventitious virus
Errantivirus
Endogenous viral element
Maverick/Polinton/Polintovirus
Spodoptera frugiperda Sf-RVN
Massively parallel sequencing
Online Access:http://link.springer.com/article/10.1186/s12896-017-0412-z

Internet

http://link.springer.com/article/10.1186/s12896-017-0412-z

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