Population pharmacokinetic modelling of primaquine exposures in lactating women and breastfed infants
Abstract Current guidelines advise against primaquine treatment for breastfeeding mothers to avoid the potential for haemolysis in infants with G6PD deficiency. To predict the haemolytic risk, the amount of drug received from the breast milk and the resulting infant drug exposure need to be characte...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-05-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-024-47908-y |