The Role of Orientation of Surface Bound Dihydropyrrol-2-ones (DHP) on Biological Activity

The Role of Orientation of Surface Bound Dihydropyrrol-2-ones (DHP) on Biological Activity

Quorum sensing (QS) signaling system is important for bacterial growth, adhesion, and biofilm formation resulting in numerous infectious diseases. Dihydropyrrol-2-ones (DHPs) represent a novel class of antimicrobial agents that inhibit QS, and are less prone to develop bacterial resistance due to th...

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Bibliographic Details
Main Authors: Aditi Taunk, Renxun Chen, George Iskander, Kitty K. K. Ho, Basmah Almohaywi, David StClair Black, Mark D. P. Willcox, Naresh Kumar
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Molecules
Subjects:
quorum sensing
surface attachment
<i>Pseudomonas</i>
<i>Staphylococcus</i>
antimicrobial
biomaterials
Online Access:https://www.mdpi.com/1420-3049/24/14/2676

Internet

https://www.mdpi.com/1420-3049/24/14/2676

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