PacBio long-read amplicon sequencing enables scalable high-resolution population allele typing of the complex CYP2D6 locus

PacBio long-read amplicon sequencing enables scalable high-resolution population allele typing of the complex CYP2D6 locus

PLASTER is a broadly-applicable data processing pipeline that enables robust allele typing of SMRT-sequenced amplicons, as evidenced by allele typing of the CYP2D6 gene in a cohort from the Solomon Islands.

Bibliographic Details
Main Authors: Sarah Charnaud, Jacob E. Munro, Lucie Semenec, Ramin Mazhari, Jessica Brewster, Caitlin Bourke, Shazia Ruybal-Pesántez, Robert James, Dulcie Lautu-Gumal, Harin Karunajeewa, Ivo Mueller, Melanie Bahlo
Format: Article
Language:English
Published: Nature Portfolio 2022-02-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03102-8

Internet

https://doi.org/10.1038/s42003-022-03102-8

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