PacBio long-read amplicon sequencing enables scalable high-resolution population allele typing of the complex CYP2D6 locus
PLASTER is a broadly-applicable data processing pipeline that enables robust allele typing of SMRT-sequenced amplicons, as evidenced by allele typing of the CYP2D6 gene in a cohort from the Solomon Islands.
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-02-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-022-03102-8 |
| _version_ | 1828751517426909184 |
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| author | Sarah Charnaud Jacob E. Munro Lucie Semenec Ramin Mazhari Jessica Brewster Caitlin Bourke Shazia Ruybal-Pesántez Robert James Dulcie Lautu-Gumal Harin Karunajeewa Ivo Mueller Melanie Bahlo |
| author_facet | Sarah Charnaud Jacob E. Munro Lucie Semenec Ramin Mazhari Jessica Brewster Caitlin Bourke Shazia Ruybal-Pesántez Robert James Dulcie Lautu-Gumal Harin Karunajeewa Ivo Mueller Melanie Bahlo |
| author_sort | Sarah Charnaud |
| collection | DOAJ |
| description | PLASTER is a broadly-applicable data processing pipeline that enables robust allele typing of SMRT-sequenced amplicons, as evidenced by allele typing of the CYP2D6 gene in a cohort from the Solomon Islands. |
| first_indexed | 2024-12-10T20:54:35Z |
| format | Article |
| id | doaj.art-1253400878aa4613b58d44f5bfe36819 |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-12-10T20:54:35Z |
| publishDate | 2022-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-1253400878aa4613b58d44f5bfe368192022-12-22T01:34:00ZengNature PortfolioCommunications Biology2399-36422022-02-015111010.1038/s42003-022-03102-8PacBio long-read amplicon sequencing enables scalable high-resolution population allele typing of the complex CYP2D6 locusSarah Charnaud0Jacob E. Munro1Lucie Semenec2Ramin Mazhari3Jessica Brewster4Caitlin Bourke5Shazia Ruybal-Pesántez6Robert James7Dulcie Lautu-Gumal8Harin Karunajeewa9Ivo Mueller10Melanie Bahlo11Walter and Eliza Hall Institute of Medical ResearchWalter and Eliza Hall Institute of Medical ResearchWalter and Eliza Hall Institute of Medical ResearchWalter and Eliza Hall Institute of Medical ResearchWalter and Eliza Hall Institute of Medical ResearchWalter and Eliza Hall Institute of Medical ResearchWalter and Eliza Hall Institute of Medical ResearchWalter and Eliza Hall Institute of Medical ResearchWalter and Eliza Hall Institute of Medical ResearchWalter and Eliza Hall Institute of Medical ResearchWalter and Eliza Hall Institute of Medical ResearchWalter and Eliza Hall Institute of Medical ResearchPLASTER is a broadly-applicable data processing pipeline that enables robust allele typing of SMRT-sequenced amplicons, as evidenced by allele typing of the CYP2D6 gene in a cohort from the Solomon Islands.https://doi.org/10.1038/s42003-022-03102-8 |
| spellingShingle | Sarah Charnaud Jacob E. Munro Lucie Semenec Ramin Mazhari Jessica Brewster Caitlin Bourke Shazia Ruybal-Pesántez Robert James Dulcie Lautu-Gumal Harin Karunajeewa Ivo Mueller Melanie Bahlo PacBio long-read amplicon sequencing enables scalable high-resolution population allele typing of the complex CYP2D6 locus Communications Biology |
| title | PacBio long-read amplicon sequencing enables scalable high-resolution population allele typing of the complex CYP2D6 locus |
| title_full | PacBio long-read amplicon sequencing enables scalable high-resolution population allele typing of the complex CYP2D6 locus |
| title_fullStr | PacBio long-read amplicon sequencing enables scalable high-resolution population allele typing of the complex CYP2D6 locus |
| title_full_unstemmed | PacBio long-read amplicon sequencing enables scalable high-resolution population allele typing of the complex CYP2D6 locus |
| title_short | PacBio long-read amplicon sequencing enables scalable high-resolution population allele typing of the complex CYP2D6 locus |
| title_sort | pacbio long read amplicon sequencing enables scalable high resolution population allele typing of the complex cyp2d6 locus |
| url | https://doi.org/10.1038/s42003-022-03102-8 |
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