Cerebral perfusion metrics calculated directly from a hypoxia-induced step change in deoxyhemoglobin

Abstract Resting cerebral perfusion metrics can be calculated from the MRI ΔR2* signal during the first passage of an intravascular bolus of a Gadolinium-based contrast agent (GBCA), or more recently, a transient hypoxia-induced change in the concentration of deoxyhemoglobin ([dOHb]). Conventional a...

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Bibliographic Details
Main Authors: James Duffin, Ece Su Sayin, Olivia Sobczyk, Julien Poublanc, David J. Mikulis, Joseph A. Fisher
Format: Article
Language:English
Published: Nature Portfolio 2024-07-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-68047-w