Reduction of VLDL secretion decreases cholesterol excretion in niemann-pick C1-like 1 hepatic transgenic mice.

Reduction of VLDL secretion decreases cholesterol excretion in niemann-pick C1-like 1 hepatic transgenic mice.

An effective way to reduce LDL cholesterol, the primary risk factor of atherosclerotic cardiovascular disease, is to increase cholesterol excretion from the body. Our group and others have recently found that cholesterol excretion can be facilitated by both hepatobiliary and transintestinal pathways...

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Bibliographic Details
Main Authors: Stephanie M Marshall, Kathryn L Kelley, Matthew A Davis, Martha D Wilson, Allison L McDaniel, Richard G Lee, Rosanne M Crooke, Mark J Graham, Lawrence L Rudel, J Mark Brown, Ryan E Temel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3880293?pdf=render

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http://europepmc.org/articles/PMC3880293?pdf=render

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