Strontium Regulates the Proliferation and Differentiation of Isolated Primary Bovine Chondrocytes via the TGFβ/SMAD Pathway

Strontium Regulates the Proliferation and Differentiation of Isolated Primary Bovine Chondrocytes via the TGFβ/SMAD Pathway

The present study evaluated the effects of strontium (Sr) on proliferation and differentiation of chondrocytes isolated from dairy cows, and whether Sr exerts its effects via transforming growth factor β (TGFβ) signaling. The chondrocytes were isolated from patellar cartilage from newborn Holstein b...

Full description

Bibliographic Details
Main Authors: Siqi Liu, Bingyu Shen, Juan J. Loor, Qianming Jiang, Yang Yuan, Yezi Kong, Panpan Tan, Fangyuan Zeng, Chenxu Zhao, Xiaoyan Zhu, Jianguo Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Pharmacology
Subjects:
strontium
bovine chondrocyte
proliferation and differentiation
TGFβ
Smad3
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.925302/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.925302/full

Similar Items