Interfering with reconsolidation by rimonabant results in blockade of heroin-associated memory

Interfering with reconsolidation by rimonabant results in blockade of heroin-associated memory

Drug-associated pathological memory remains a critical factor contributing to the persistence of substance use disorder. Pharmacological amnestic manipulation to interfere with drug memory reconsolidation has shown promise for the prevention of relapse. In a rat heroin self-administration model, we...

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Bibliographic Details
Main Authors: Jiang Lin, Yilin Peng, Jinlong Zhang, Junzhe Cheng, Qianqian Chen, Binbin Wang, Yuhang Liu, Shuliang Niu, Jie Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Pharmacology
Subjects:
reconsolidation
heroin-associated memory
rimonabant
relapse
heroin-seeking
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1361838/full

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https://www.frontiersin.org/articles/10.3389/fphar.2024.1361838/full

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