Janus kinase inhibitors: jackpot or potluck?

The reports of a unique mutation in the Janus kinase-2 gene (JAK2) in polycythemia vera by several independent groups in 2005 quickly spurred the development of the Janus kinase inhibitors. In one of the great victories of translational research in recent times, the first smallmolecule Janus kinase...

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Bibliographic Details
Main Authors: Pavithran Keechilat, Shripad Brahmanand Pande
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-06-01
Series:Oncology Reviews
Subjects:
Online Access:http://www.oncologyreviews.org/index.php/or/article/view/187