Super-resolution imaging for in situ monitoring sub-cellular micro-dynamics of small molecule drug

Super-resolution imaging for in situ monitoring sub-cellular micro-dynamics of small molecule drug

Small molecule drugs play a pivotal role in the arsenal of anticancer pharmacological agents. Nonetheless, their small size poses a challenge when directly visualizing their localization, distribution, mechanism of action (MOA), and target engagement at the subcellular level in real time. We propose...

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Bibliographic Details
Main Authors: Huimin Chen, Guiqian Fang, Youxiao Ren, Weiwei Zou, Kang Ying, Zhiwei Yang, Qixin Chen
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Mitochondrial
Drug beacon
Sub-cellular
Small molecule
Energy supply
Anti-tumor
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383523004458

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http://www.sciencedirect.com/science/article/pii/S2211383523004458

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