EspC, an Autotransporter Protein Secreted by Enteropathogenic <named-content content-type="genus-species">Escherichia coli</named-content>, Causes Apoptosis and Necrosis through Caspase and Calpain Activation, Including Direct Procaspase-3 Cleavage

ABSTRACT Enteropathogenic Escherichia coli (EPEC) has the ability to antagonize host apoptosis during infection through promotion and inhibition of effectors injected by the type III secretion system (T3SS), but the total number of these effectors and the overall functional relationships between the...

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Bibliographic Details
Main Authors: Antonio Serapio-Palacios, Fernando Navarro-Garcia
Format: Article
Language:English
Published: American Society for Microbiology 2016-07-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00479-16