Implications of Rho GTPase signaling in glioma cell invasion and tumor progression

Glioblastoma (GB) is the most malignant of primary adult brain tumors, characterized by a highly locally-invasive cell population, as well as abundant proliferative cells, neoangiogenesis, and necrosis. Clinical intervention with chemotherapy or radiation may either promote or establish an environme...

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Bibliographic Details
Main Authors: Shannon Patricia Fortin Ensign, Ian eMathews, Marc eSymons, Michael eBerens, Nhan Le Tran
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00241/full