Implications of Rho GTPase signaling in glioma cell invasion and tumor progression

Implications of Rho GTPase signaling in glioma cell invasion and tumor progression

Glioblastoma (GB) is the most malignant of primary adult brain tumors, characterized by a highly locally-invasive cell population, as well as abundant proliferative cells, neoangiogenesis, and necrosis. Clinical intervention with chemotherapy or radiation may either promote or establish an environme...

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Bibliographic Details
Main Authors: Shannon Patricia Fortin Ensign, Ian eMathews, Marc eSymons, Michael eBerens, Nhan Le Tran
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Oncology
Subjects:
Glioblastoma
Survival
Rac1
Cdc42
RhoA
GEFs
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00241/full

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