Deep Vein Thrombosis Is Facilitated by Endothelial-Derived Extracellular Vesicles via the PDI–GRP94–GPIIb/IIIa Pathway in Mice

Deep Vein Thrombosis Is Facilitated by Endothelial-Derived Extracellular Vesicles via the PDI–GRP94–GPIIb/IIIa Pathway in Mice

Aims: Deep vein thrombosis (DVT) is a prevalent cardiovascular condition. Endothelial-derived extracellular vesicles (EVs) may play a crucial role in platelet-dependent DVT development via platelet activation, but the mechanism is not clear yet. This research aims to understand how platelets and end...

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Bibliographic Details
Main Authors: Hongtao Lan, Zhoujie Tong, Yaqiong Jiao, Haitao Han, Ying Ma, Yulin Li, Xu Jia, Boang Hu, Wei Zhang, Ming Zhong, Zhihao Wang
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Journal of Clinical Medicine
Subjects:
platelet
endothelial-derived extracellular vesicles
deep vein thrombosis
protein disulfide isomerase
Online Access:https://www.mdpi.com/2077-0383/12/13/4265

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https://www.mdpi.com/2077-0383/12/13/4265

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