Tempol Protects Against Acute Renal Injury by Regulating PI3K/Akt/mTOR and GSK3β Signaling Cascades and Afferent Arteriolar Activity

Tempol Protects Against Acute Renal Injury by Regulating PI3K/Akt/mTOR and GSK3β Signaling Cascades and Afferent Arteriolar Activity

Background/Aims: Free radical scavenger tempol is a protective antioxidant against ischemic injury. Tubular epithelial apoptosis is one of the main changes in the renal ischemia/reperfusion (I/R) injury. Meanwhile some proteins related with apoptosis and inflammation are also involved in renal I/R i...

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Bibliographic Details
Main Authors: Gensheng Zhang, Qin Wang, Wenwen Wang, Minghua Yu, Suping Zhang, Nan Xu, Suhan Zhou, Xiaoyun Cao, Xiaodong Fu, Zufu Ma, Ruisheng Liu, Jianhua Mao, En Yin Lai
Format: Article
Language:English
Published: Karger Publishers 2018-05-01
Series:Kidney & Blood Pressure Research
Subjects:
Acute kidney injury
Ischemia/reperfusion
Tempol
Afferent arteriole
Online Access:https://www.karger.com/Article/FullText/490338

Internet

https://www.karger.com/Article/FullText/490338

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