Antagonism of the prostaglandin D<sub>2 </sub>receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation

Antagonism of the prostaglandin D<sub>2 </sub>receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation

<p>Abstract</p> <p>Background</p> <p>Mast cell-derived prostaglandin D<sub>2 </sub>(PGD<sub>2</sub>), may contribute to eosinophilic inflammation and mucus production in allergic asthma. Chemoattractant receptor homologous molecule expressed on T...

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Bibliographic Details
Main Authors: Högberg Thomas, Ulven Trond, Korsgren Magnus, Alenmyr Lisa, Mathiesen Jesper, Uller Lena, Andersson Gunnar, Persson Carl GA, Kostenis Evi
Format: Article
Language:English
Published: BMC 2007-02-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/8/1/16

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http://respiratory-research.com/content/8/1/16

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