Microbe-Mediated Activation of Toll-like Receptor 2 Drives PDL1 Expression in HNSCC

As immunotherapies targeting the PDL1 checkpoint have become a mainstay of treatment for a subset of head and neck squamous cell carcinoma (HNSCC) patients, a detailed understanding of the mechanisms underlying PDL1-mediated immune evasion is needed. To elucidate factors regulating expression of PDL...

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Bibliographic Details
Main Authors: Jacqueline E Mann, Megan L Ludwig, Aditi Kulkarni, Erin B Scheftz, Isabel R Murray, Jingyi Zhai, Elizabeth Gensterblum-Miller, Hui Jiang, J Chad Brenner
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/19/4782