A ubiquitin ligase complex regulates caspase activation during sperm differentiation in Drosophila.
In both insects and mammals, spermatids eliminate their bulk cytoplasm as they undergo terminal differentiation. In Drosophila, this process of dramatic cellular remodeling requires apoptotic proteins, including caspases. To gain further insight into the regulation of caspases, we screened a large c...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-10-01
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| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC1976628?pdf=render |