Erxian herbal pair enhances bone formation in infected bone nonunion models and attenuates lipopolysaccharide-induced osteoblastinhibition by regulating miRNA-34a-5p

Erxian herbal pair enhances bone formation in infected bone nonunion models and attenuates lipopolysaccharide-induced osteoblastinhibition by regulating miRNA-34a-5p

ABSTRACTBacterium-induced inflammatory responses cause bone nonunion. Although antibiotics suppress infection, bone loss after antibacterial treatment remains a critical challenge. Erxian herbal pair (EHP) has been proven effective in promoting bone formation. Our study aimed to investigate the effe...

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Bibliographic Details
Main Authors: Li Zhang, Yang Zhang, Maomao Miao, Shaoqi Hu, Xuping Wang, Lisha Zhao, Xiaowen Huang, Gang Cao, Dan Shou
Format: Article
Language:English
Published: Taylor & Francis Group 2022-06-01
Series:Bioengineered
Subjects:
Erxian herbal pair
bone repair
LPS-induced bone loss
MiRNA-34a-5p
osteoblasts
Online Access:https://www.tandfonline.com/doi/10.1080/21655979.2022.2085388

Internet

https://www.tandfonline.com/doi/10.1080/21655979.2022.2085388

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