Structure-Based Modeling of Complement C4 Mediated Neutralization of Adenovirus
Adenovirus (AdV) infection elicits a strong immune response with the production of neutralizing antibodies and opsonization by complement and coagulation factors. One anti-hexon neutralizing antibody, called 9C12, is known to activate the complement cascade, resulting in the deposition of complement...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-01-01
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Series: | Viruses |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4915/13/1/111 |