Enhanced Specialized Transduction Using Recombineering in <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>

ABSTRACT Genetic engineering has contributed greatly to our understanding of Mycobacterium tuberculosis biology and has facilitated antimycobacterial and vaccine development. However, methods to generate M. tuberculosis deletion mutants remain labor-intensive and relatively inefficient. Here, method...

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Bibliographic Details
Main Authors: JoAnn M. Tufariello, Adel A. Malek, Catherine Vilchèze, Laura E. Cole, Hannah K. Ratner, Pablo A. González, Paras Jain, Graham F. Hatfull, Michelle H. Larsen, William R. Jacobs
Format: Article
Language:English
Published: American Society for Microbiology 2014-07-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.01179-14