Advantages and Applications of CAR-Expressing Natural Killer Cells

Advantages and Applications of CAR-Expressing Natural Killer Cells

In contrast to donor T cells, natural killer (NK) cells are known to mediate anti-cancer effects without the risk of inducing graft-versus-host disease (GvHD). In order to improve cytotoxicity against resistant cancer cells, auspicious efforts have been made with chimeric antigen receptor (CAR) expr...

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Bibliographic Details
Main Authors: Wolfgang eGlienke, Ruth eEsser, Christoph ePriesner, Julia eSuerth, Axel eSchambach, Winfried eWels, Manuel eGrez, Stephan eKloess, Lubomir eArseniev, Ulrike eKoehl
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Pharmacology
Subjects:
NK cells
T cells
GvHD
CAR
Suicide Genes
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00021/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00021/full

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