Both Complexity and Location of DNA Damage Contribute to Cellular Senescence Induced by Ionizing Radiation.

Persistent DNA damage is considered as a main cause of cellular senescence induced by ionizing radiation. However, the molecular bases of the DNA damage and their contribution to cellular senescence are not completely clear. In this study, we found that both heavy ions and X-rays induced senescence...

Full description

Bibliographic Details
Main Authors: Xurui Zhang, Caiyong Ye, Fang Sun, Wenjun Wei, Burong Hu, Jufang Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4871470?pdf=render