SNP-based typing: a useful tool to study Bordetella pertussis populations.

To monitor changes in Bordetella pertussis populations, mainly two typing methods are used; Pulsed-Field Gel Electrophoresis (PFGE) and Multiple-Locus Variable-Number Tandem Repeat Analysis (MLVA). In this study, a single nucleotide polymorphism (SNP) typing method, based on 87 SNPs, was developed a...

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Bibliographic Details
Main Authors: Marjolein van Gent, Marieke J Bart, Han G J van der Heide, Kees J Heuvelman, Teemu Kallonen, Qiushui He, Jussi Mertsola, Abdolreza Advani, Hans O Hallander, Koen Janssens, Peter W Hermans, Frits R Mooi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3103551?pdf=render