V-Domain Ig Suppressor of T Cell Activation (VISTA) Expression Is an Independent Prognostic Factor in Multiple Myeloma

V-Domain Ig Suppressor of T Cell Activation (VISTA) Expression Is an Independent Prognostic Factor in Multiple Myeloma

Multiple myeloma (MM) is characterized by loss of anti-tumor T cell immunity. Despite moderate success of treatment with anti-PD1 antibodies, effective treatment is still challenged by poor T cell-mediated control of MM. To better enable identification of shortcomings in T-cell immunity that relate...

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Bibliographic Details
Main Authors: Pim Mutsaers, Hayri E. Balcioglu, Rowan Kuiper, Dora Hammerl, Rebecca Wijers, Mark van Duin, Bronno van der Holt, Annemiek Broijl, Walter Gregory, Sonja Zweegman, Pieter Sonneveld, Reno Debets
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
multiple myeloma
tumor immunology
immune therapy
V-domain Ig suppressor of T cell activation (VISTA)
immune checkpoints
Online Access:https://www.mdpi.com/2072-6694/13/9/2219

Internet

https://www.mdpi.com/2072-6694/13/9/2219

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