Integrin α9 regulates smooth muscle cell phenotype switching and vascular remodeling
Excessive proliferation of vascular smooth muscle cells (SMCs) remains a significant cause of in-stent restenosis. Integrins, which are heterodimeric transmembrane receptors, play a crucial role in SMC biology by binding to the extracellular matrix protein with the actin cytoskeleton within the SMC....
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Clinical investigation
2021-05-01
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Series: | JCI Insight |
Subjects: | |
Online Access: | https://doi.org/10.1172/jci.insight.147134 |