Vascular Endothelial Growth Factor Augments Arginine Transport and Nitric Oxide Generation via a KDR Receptor Signaling Pathway

Vascular Endothelial Growth Factor Augments Arginine Transport and Nitric Oxide Generation via a KDR Receptor Signaling Pathway

Background/Aims: Vascular endothelial growth factor (VEGF) is an endothelium-specific peptide that stimulates angiogenesis via two receptor tyrosine kinases, Flt-1 and KDR. Endothelial nitric oxide synthase (eNOS) plays a major role in VEGF signaling. Delivery of arginine to membrane bound eNOS by t...

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Bibliographic Details
Main Authors: Moshe Shashar, Tamara Chernichovski, Oren Pasvolsky, Sharon Levi, Ayelet Grupper, Rami Hershkovitz, Talia Weinstein, Idit F. Schwartz
Format: Article
Language:English
Published: Karger Publishers 2017-05-01
Series:Kidney & Blood Pressure Research
Subjects:
Arginine transport
VEGF
Nitric Oxide
Online Access:http://www.karger.com/Article/FullText/476016

Internet

http://www.karger.com/Article/FullText/476016

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