Evaluation of solid-lipid nanoparticles formulation of methotrexate for anti-psoriatic activity

Evaluation of solid-lipid nanoparticles formulation of methotrexate for anti-psoriatic activity

Background & Objectives: Methotrexate (MTX) is commonly used to manage psoriasis. The drug has erratic absorption characteristics and shows several complications. The present study uses different experimental models to evaluate the solid-lipid nanoparticles of MTX (SLN-MTX) for the anti-psor...

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Bibliographic Details
Main Authors: Debarati Maiti, Mohammed Naseeruddin Inamdar, Mansour Almuqbil, Sarasija Suresh, Syed Mohammed Basheeruddin Asdaq, Sultan Alshehri, Saad Ali Al Arfaj, Ali Musharraf Alamri, Meshal Meshary Aldohyan, Misfir Theeb Alqahtani, Turki Mohammed Alosaimi, Sami Haran Alenazi, Moneer E. Almadani, Jameel Ahmed S. Mulla, Syed Imam Rabbani
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Saudi Pharmaceutical Journal
Subjects:
Solid-lipid nanoparticles
Methotrexate
Permeability
Distribution
Keratinocytes
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016423000890

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http://www.sciencedirect.com/science/article/pii/S1319016423000890

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