Novel Toll-like receptor-4 deficiency attenuates trastuzumab (Herceptin) induced cardiac injury in mice

Novel Toll-like receptor-4 deficiency attenuates trastuzumab (Herceptin) induced cardiac injury in mice

<p>Abstract</p> <p>Background</p> <p>Cardiac inflammation and generation of oxidative stress are known to contribute to trastuzumab (herceptin) induced cardiac toxicity. Toll-like receptors (TLRs) are a part of the innate immune system and are involved in cardiac stress...

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Bibliographic Details
Main Authors: Yousif Nasser, Al-amran Fadhil G
Format: Article
Language:English
Published: BMC 2011-10-01
Series:BMC Cardiovascular Disorders
Subjects:
Toll Like Receptor 4
cardiac-toxicity
Inflammation
trastuzumab
Online Access:http://www.biomedcentral.com/1471-2261/11/62

Internet

http://www.biomedcentral.com/1471-2261/11/62

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