IL‐23R Deficiency Does Not Impact Atherosclerotic Plaque Development in Mice

IL‐23R Deficiency Does Not Impact Atherosclerotic Plaque Development in Mice

BackgroundInterleukin‐23 (IL‐23) has been implicated in inflammatory and autoimmune diseases by skewing CD4+ T helper cells towards a pathogenic Th17 phenotype. In this study we investigated the presence of IL‐23 receptor (IL‐23R)‐expressing cells in the atherosclerotic aorta and evaluated the effec...

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Bibliographic Details
Main Authors: Daniel Engelbertsen, Marie A. C. Depuydt, Robin A. F. Verwilligen, Sara Rattik, Erik Levinsohn, Andreas Edsfeldt, Felicia Kuperwaser, Petr Jarolim, Andrew H. Lichtman
Format: Article
Language:English
Published: Wiley 2018-04-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
atherosclerosis
IL‐23R
lymphocyte
Th17
IL‐17
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.117.008257

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.117.008257

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