GALNT3 Maintains the Epithelial State in Trophoblast Stem Cells

Summary: O-GalNAc glycosylation is initiated in the Golgi by glycosyltransferases called GALNTs. Proteomic screens identified >600 O-GalNAc-modified proteins, but the biological relevance of these modifications has been difficult to determine. We have discovered a conserved function for GALNT3 in...

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Bibliographic Details
Main Authors: Deepthi Raghu, Robert J. Mobley, Noha A.M. Shendy, Charles H. Perry, Amy N. Abell
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719302797