Comprehensive pan-cancer genomic landscape of KRAS altered cancers and real-world outcomes in solid tumors

Comprehensive pan-cancer genomic landscape of KRAS altered cancers and real-world outcomes in solid tumors

Abstract Recent clinical development of KRAS inhibitors has heightened interest in the genomic landscape of KRAS-altered cancers. We performed a pan-cancer analysis of KRAS-altered samples from 426,706 adult patients with solid or hematologic malignancies using comprehensive genomic profiling; addit...

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Bibliographic Details
Main Authors: Jessica K. Lee, Smruthy Sivakumar, Alexa B. Schrock, Russell Madison, David Fabrizio, Ole Gjoerup, Jeffrey S. Ross, Garrett M. Frampton, Pavel Napalkov, Meagan Montesion, Jennifer L. Schutzman, Xin Ye, Priti S. Hegde, Misako Nagasaka, Geoffrey R. Oxnard, Ethan S. Sokol, Sai-Hong Ignatius Ou, Zhen Shi
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-022-00334-z

Internet

https://doi.org/10.1038/s41698-022-00334-z

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