Scalable Microbial Strain Inference in Metagenomic Data Using StrainFacts

Scalable Microbial Strain Inference in Metagenomic Data Using StrainFacts

While genome databases are nearing a complete catalog of species commonly inhabiting the human gut, their representation of intraspecific diversity is lacking for all but the most abundant and frequently studied taxa. Statistical deconvolution of allele frequencies from shotgun metagenomic data into...

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Bibliographic Details
Main Authors: Byron J. Smith, Xiangpeng Li, Zhou Jason Shi, Adam Abate, Katherine S. Pollard
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Bioinformatics
Subjects:
metagenomics
strains
microbiome
biogeography
population genetics
model-based inference
Online Access:https://www.frontiersin.org/articles/10.3389/fbinf.2022.867386/full

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https://www.frontiersin.org/articles/10.3389/fbinf.2022.867386/full

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