SCReadCounts: estimation of cell-level SNVs expression from scRNA-seq data

SCReadCounts: estimation of cell-level SNVs expression from scRNA-seq data

Abstract Background Recent studies have demonstrated the utility of scRNA-seq SNVs to distinguish tumor from normal cells, characterize intra-tumoral heterogeneity, and define mutation-associated expression signatures. In addition to cancer studies, SNVs from single cells have been useful in studies...

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Bibliographic Details
Main Authors: N. M. Prashant, Nawaf Alomran, Yu Chen, Hongyu Liu, Pavlos Bousounis, Mercedeh Movassagh, Nathan Edwards, Anelia Horvath
Format: Article
Language:English
Published: BMC 2021-09-01
Series:BMC Genomics
Subjects:
SNV
SNP
scRNA-seq
Mutation
Somatic mutation
Allele
Online Access:https://doi.org/10.1186/s12864-021-07974-8

Internet

https://doi.org/10.1186/s12864-021-07974-8

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