Traditional Chinese Medicine Shi-Bi-Man ameliorates psoriasis via inhibiting IL-23/Th17 axis and CXCL16-mediated endothelial activation

Traditional Chinese Medicine Shi-Bi-Man ameliorates psoriasis via inhibiting IL-23/Th17 axis and CXCL16-mediated endothelial activation

Abstract Background Psoriasis is a chronic inflammatory genetic disease, mainly manifesting in the skin. Conventional therapies, such as glucocorticosteroids and corticosteroids, have adverse effects that limit drug use. Hence, it is imperative to identify a new therapeutic strategy that exhibits a...

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Bibliographic Details
Main Authors: Chenyang Zhang, Xinran Cao, Lixin Zhao, Zitong Ni, Haojie Du, Jiao Qu, Jianxia Zhu, Haiyan Sun, Yang Sun, Zijun Ouyang
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Chinese Medicine
Subjects:
Psoriasis
IL-23
Th17 axis
Single-cell RNA sequencing
Endothelial cell
Online Access:https://doi.org/10.1186/s13020-024-00907-z

Internet

https://doi.org/10.1186/s13020-024-00907-z

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