EZH2-Inhibited MicroRNA-454-3p Promotes M2 Macrophage Polarization in Glioma

Glioma is a primary intracranial tumor with high incidence and mortality. The oncogenic role of EZH2 has been reported in glioma. EZH2 inhibited microRNA-454-3p (miR-454-3p) by binding to its promoter in chondrosarcoma cells. Therefore, our study aimed to identify whether EZH2 regulated M2 macrophag...

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Bibliographic Details
Main Authors: Bin Qi, Cheng Yang, Zhanpeng Zhu, Hao Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.574940/full