WNK4 is an Adipogenic Factor and Its Deletion Reduces Diet-Induced Obesity in Mice

WNK4 is an Adipogenic Factor and Its Deletion Reduces Diet-Induced Obesity in Mice

The with-no-lysine kinase (WNK) 4 gene is a causative gene in pseudohypoaldosteronism type II. Although WNKs are widely expressed in the body, neither their metabolic functions nor their extrarenal role is clear. In this study, we found that WNK4 was expressed in mouse adipose tissue and 3T3-L1 adip...

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Bibliographic Details
Main Authors: Daiei Takahashi, Takayasu Mori, Eisei Sohara, Miyako Tanaka, Motoko Chiga, Yuichi Inoue, Naohiro Nomura, Moko Zeniya, Hiroki Ochi, Shu Takeda, Takayoshi Suganami, Tatemitsu Rai, Shinichi Uchida
Format: Article
Language:English
Published: Elsevier 2017-04-01
Series:EBioMedicine
Subjects:
WNK4
Hypertension
Metabolic syndrome
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396417300981

Internet

http://www.sciencedirect.com/science/article/pii/S2352396417300981

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