Inhibition of Heme Polymerization, the Mechanism of Antimalarial Activity in Phlomis caucasica Rech.f. (Lamiaceae)

Background: Malaria is one of the most important parasitic diseases in the world caused by Plasmodium species. The malaria parasite digests hemoglobin in vacuole to amino acids and heme. Plasmodium has got several detoxification mechanisms to protect itself from toxic heme. The most important mechan...

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Bibliographic Details
Main Authors: Somayeh Esmaeili, Mahboubeh Irani, Hamid Moazzeni, Mahmoud Mosaddegh
Format: Article
Language:English
Published: Institue of Medicinal Plants, ACECR 2019-12-01
Series:Journal of Medicinal Plants
Subjects:
Online Access:http://jmp.ir/article-1-2278-en.html