Mechano-biological and bio-mechanical pathways in cutaneous wound healing.

Injuries to the skin heal through coordinated action of fibroblast-mediated extracellular matrix (ECM) deposition, ECM remodeling, and wound contraction. Defects involving the dermis result in fibrotic scars featuring increased stiffness and altered collagen content and organization. Although comput...

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Bibliographic Details
Main Authors: Marco Pensalfini, Adrian Buganza Tepole
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-03-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010902