Profiling protease cleavage patterns in plasma for pancreatic cancer detection
Abstract Proteases are promising biomarkers for cancer early detection. Their enzymatic activity against peptide substrates allows for their straightforward detection using low-cost tests. However, the complexity of the human proteome makes it challenging to develop sensitive and selective tests aga...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-12-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-024-83077-0 |