The International Collaborative Gaucher Group GRAF (Gaucher Risk Assessment for Fracture) score: a composite risk score for assessing adult fracture risk in imiglucerase-treated Gaucher disease type 1 patients

The International Collaborative Gaucher Group GRAF (Gaucher Risk Assessment for Fracture) score: a composite risk score for assessing adult fracture risk in imiglucerase-treated Gaucher disease type 1 patients

Abstract Background Fractures in Gaucher disease type 1 (GD1) patients cause significant morbidity. Fracture risk may be decreased by enzyme replacement therapy (ERT) but not eliminated. When considering initiation of treatment, it is useful to know to what extent fixed patient-specific factors dete...

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Bibliographic Details
Main Authors: Patrick Deegan, Aneal Khan, José Simon Camelo, Julie L. Batista, Neal Weinreb
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Orphanet Journal of Rare Diseases
Subjects:
Gaucher disease
Fracture
Imiglucerase
Enzyme replacement therapy
Risk factor
Online Access:https://doi.org/10.1186/s13023-020-01656-6

Internet

https://doi.org/10.1186/s13023-020-01656-6

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