YB1 dephosphorylation attenuates atherosclerosis by promoting CCL2 mRNA decay

YB1 dephosphorylation attenuates atherosclerosis by promoting CCL2 mRNA decay

Chronic inflammation is a key pathological process in atherosclerosis. RNA binding proteins (RBPs) have been reported to play an important role in atherosclerotic plaque formation, and they could regulate the expression of inflammatory factors by phosphorylation modification. Y-box binding protein 1...

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Bibliographic Details
Main Authors: Yaqin Tang, Zhiwei Li, Hongqin Yang, Yang Yang, Chi Geng, Bin Liu, Tiantian Zhang, Siyang Liu, Yunfei Xue, Hongkai Zhang, Jing Wang, Hongmei Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
atherosclerosis
RNA binding protein
phosphorylation
inflammation
mRNA decay
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.945557/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2022.945557/full

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