Loss of POMC-mediated antinociception contributes to painful diabetic neuropathy
Proopiomelanocortin is an anti-nociceptive peptide. Here the authors show in a mouse model of diabetes, that this peptide is downregulated, which may contribute to the neuropathic pain like behaviour in these models.
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-01-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-20677-0 |