Susceptibility to hormone-mediated cancer is reflected by different tick rates of the epithelial and general epigenetic clock

Susceptibility to hormone-mediated cancer is reflected by different tick rates of the epithelial and general epigenetic clock

Abstract Background A variety of epigenetic clocks utilizing DNA methylation changes have been developed; these clocks are either tissue-independent or designed to predict chronological age based on blood or saliva samples. Whether discordant tick rates between tissue-specific and general epigenetic...

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Main Authors: James E. Barrett, Chiara Herzog, Yoo-Na Kim, Thomas E. Bartlett, Allison Jones, Iona Evans, David Cibula, Michal Zikan, Line Bjørge, Nadia Harbeck, Nicoletta Colombo, Sacha J. Howell, Angelique Flöter Rådestad, Kristina Gemzell-Danielsson, Martin Widschwendter
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-022-02603-3

Internet

https://doi.org/10.1186/s13059-022-02603-3

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