Microglia-derived exosomal circZNRF1 alleviates paraquat-induced neuronal cell damage via miR-17-5p

Microglia-derived exosomal circZNRF1 alleviates paraquat-induced neuronal cell damage via miR-17-5p

Paraquat (PQ) is an environmental poison that causes clinical symptoms similar to those of Parkinson's disease (PD) in vitro and in rodents. It can lead to the activation of microglia and apoptosis of dopaminergic neurons. However, the exact role and mechanism of microglial activation in PQ-ind...

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Bibliographic Details
Main Authors: Xu Liu, Qingqing Wu, Jingwen Wu, Jianxi Liu, Fuli Zheng, Guangxia Yu, Hong Hu, Zhenkun Guo, Siying Wu, Huangyuan Li, Wenya Shao
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Exosome
Circular RNA
Apoptosis
Parkinson's disease
Paraquat
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323008606

Internet

http://www.sciencedirect.com/science/article/pii/S0147651323008606

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