Long Non-coding RNAs Gabarapl2 and Chrnb2 Positively Regulate Inflammatory Signaling in a Mouse Model of Dry Eye

Long Non-coding RNAs Gabarapl2 and Chrnb2 Positively Regulate Inflammatory Signaling in a Mouse Model of Dry Eye

Purpose: To elucidate the expression profile and the potential role of long non-coding ribonucleic acids (RNAs) (lncRNAs) in a dry eye disease (DED) model.Methods: A DED model was established in C57BL/6J mice with 0.2% benzalkonium chloride (BAC) twice a day for 14 days. The differentially expressed...

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Bibliographic Details
Main Authors: Yuhan Yang, Minjie Chen, Zimeng Zhai, Yiqin Dai, Hao Gu, Xujiao Zhou, Jiaxu Hong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Medicine
Subjects:
long non-coding RNA (lncRNA)
Gabarapl2 and Chrnb2
dry eye disease (DED)
neuroactive ligand–receptor interaction signaling
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.808940/full

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https://www.frontiersin.org/articles/10.3389/fmed.2021.808940/full

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