Rational application of targeted therapeutics in mucinous colon/appendix cancers with positive predictive factors

Abstract Molecular‐targeted therapies have demonstrated disappointing results against most advanced solid cancers. This may largey be attributed to irrational drug use against unselected cancers. We investigated the efficacy of dual MEK‐PI3K drug therapy against KRAS mutated mucin 2 (MUC2)‐secreting...

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Bibliographic Details
Main Authors: Ashokkumar Dilly, Brendon D. Honick, Yong J. Lee, David L. Bartlett, Haroon A. Choudry
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.2847